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James Brewer, M.D., Ph.D.
Assistant Professor, Radiology and Neurosciences
Human Memory Laboratory
LJVPC Suite C212, MC 0949
La Jolla, CA 92093-0949
office tel: 858-534-1237
lab tel: 858-534-1227
Fax: 858-534-1240
Email: jbrewerATucsd.edu
Lab Website: http://hml.ucsd.edu/hml/ |
| High-Resolution Functional Imaging of Human Memory Processes |
| Our laboratory uses functional and structural magnetic resonance imaging (MRI) to study memory processes in volunteers with healthy memory and in patients with memory difficulties, such as in Alzheimer’s disease (AD). This research focuses upon the medial temporal lobe (MTL), which shows selective damage early in the course of AD. The laboratory studies the contributions to memory that are made by distinct MTL substructures and the interaction of these structures with other brain regions. |
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Brewer JB and Moghekar A. (2002). Imaging the medial temporal lobe: exploring new dimensions. Trends in Cognitive Science, 6, 217-223.
Golby, AJ, Poldrack RA, Brewer JB, Spencer D, Desmond JE, Aron A P, Gabrieli JDE. (2001). Material-specific lateralization in the medial temporal lobe and prefrontal cortex during memory encoding. Brain, 124, 1841-1854.
Canli T, Zhao Z, Brewer JB, Gabrieli JD, Cahill L. (2000). Event-related activation in the human amygdala associates with later memory for individual emotional experience. Journal of Neuroscience. 20, RC99
Fernandez G, Brewer JB, Zhao Z, Glover GH, Gabrieli JD. (1999). Level of sustained entorhinal activity at study correlates with subsequent cued-recall performance: a functional magnetic resonance imaging study with high acquisition rate. Hippocampus, 9, 35-44.
Gabrieli JDE, Brewer JB, Poldrack RA (1998). Images of medial temporal lobe function in human learning and memory. Neurobiology of Learning and Memory, 70, 275-283.
Brewer JB, Zhao Z, Desmond JE, Glover GH, Gabrieli JD (1998). Making Memories: brain activity that predicts how well visual experience will be remembered. Science, 281, 1185-1187.
Brewer JB, Gabrieli JD (1997). Focusing in on the medial temporal lobe. Molecular Psychiatry, 2, 427-431.
Gabrieli JDE, Brewer JB, Desmond JE, Glover GH (1997). Separate neural bases of two fundamental memory processes in the human medial temporal lobe. Science, 276, 264-266.
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