University of California - San Diego
UCSD - Neurosciences Graduate Program

THE DOCTORAL PROGRAM REQUIREMENTS

Students must complete the following requirements to obtain the Degree of Doctor of Philosophy:

Boot Camp

Boot Camp is an intense pre-graduate laboratory course, intended mainly for the incoming first year students. This course is patterned after summer courses at the Marine Biological Laboratory (MBL) in Woods Hole, MA, with a series of intensive lab exercises that run six days a week from early morning until midnight and beyond, held in September, just before regular classes begin in Fall Quarter. In addition, part of each morning is devoted to lectures by 5-7 faculty members, highlighting the major research interests being pursued in their laboratories. At lunch time, the students give short talks about the research they have done before entering this graduate program. The purposes of Boot Camp are to introduce the new students to basic ideas and techniques of neuroscience, to get them acquainted with a number of the faculty members and more senior graduate students (who serve as TAs), and for them to get to know one another. All incoming students participate in Boot Camp.

Research Rotations

Research rotations provide the opportunity for first- year students to obtain hands-on research experience in several different laboratories. A rotation generally lasts one quarter. At least three rotations must be completed by the end of the summer quarter of the student’s first year. By this time each student should have found a faculty member under whose sponsorship and in whose laboratory the dissertation research will be completed.

The student is responsible for arranging his or her own rotations and registering with the Registrar’s Office. Only Fall Quarter rotations may be scheduled before arriving in San Diego. Winter and Spring rotations may be scheduled after Boot Camp is over. The student should inform the Graduate Program Coordinator prior to starting a rotation, so that a section number can be set up for enrollment.

Prior to the beginning of the rotation, the student and faculty member should discuss what is expected. Regular meetings between the student and the faculty advisor are expected. At the conclusion of each rotation, written evaluations are submitted both by the faculty member and the student to the Graduate Program Coordinators. Students are required to present a short rotation talk on one of the three rotations at boot Camp at the end of their first year.

For MSTP Students:
MSTP students are expected to have completed at least two rotations before joining the graduate program, and must complete three rotations before joining a thesis lab. At least two of the rotations must be in labs associated with the Neurosciences Graduate Program. MSTP students must complete all rotations by Fall quarter after entering the graduate program, and must select a thesis lab by the end of the Fall quarter. The thesis advisor will take financial responsibility for the student (stipend and fees) once the student joins the lab.

Course Work

All students in the Program are required to take six Core Courses, fulfill elective requirements, attend Research Rounds for two years, complete three research rotations, and teach for at least one quarter.

Grading

Core Courses, research rounds, and required electives must be taken for a letter grade and a grade of "B" or better must be obtained. (If taking a Satisfactory/Unsatisfactory course, a letter written by the instructor stating the letter grade is sufficient.) All other courses may be taken for a grade of "satisfactory", where "satisfactory" grade is considered to be a "B-" or better. If a student receives a grade of "C+" or lower or "unsatisfactory", (s)he has the option of either repeating the course or taking a different course from the list of allowable electives.

It is the responsibility of each student to clear up any grading problems. Students should check their academic record on TritonLink each quarter for grading errors, missing grades and/or incorrect course enrollment. If grading errors are not cleared up by the end of the quarter, the grade “F” or “U” will be assigned. All academic errors must be corrected within one year.

Petitioning

Many of the academic and administrative requirements are handled by "General Petitions," as outlined in Appendix VIII of the Student Handbook. Note an important use of the General Petition, listed under section H. Other: "...may also be used when requesting exceptions to academic policy not covered in other petition sections." This means that students can petition for exceptions to essentially any policy, and these requests will be considered.

Core Courses

By the time of the Minor Proposition Exam (see p.14), students are expected to demonstrate competence in the basics of neuroscience by taking five quarters of mandatory course work:

  • NEU 200A, B, C: Core Neuroscience courses
  • NEU 225 Statistical Methods and Experimental Design
  • NEU 257 Mammalian Neuroanatomy Laboratory
  • Ethics Course Requirement

Statistical Methods & Experimental Design (NEU 225)
All first year Neurosciences students, including MSTP students, MUST register for this course. Students with prior statistical coursework that resulted in a letter grade: "A" will meet the degree requirements if they also fulfill the course requirements of the Computational Neurobiology specialization. This course is designed for graduate students in the neurosciences. The course will address principle issues of statistical methods and study design as well as selected advanced topics relating to neurosciences research. The course will combine lectures, discussion, and practical examples drawn from medical research and neurosciences.

Electives

Neurosciences Graduate Program
Electives Requirement
Students are required to take 12 credits of elective courses, at least 4 credits need to be advanced topics courses based on reading of primary literature. This can be satisfied by either by completing Neu 221 courses or by completing readings based courses offered by the Departments of Neurosciences, Biological Sciences, Cognitive Science, and Psychology. To qualify for a readings-based course, at least one session per week should be devoted to discussion of published research papers.

The remaining 8 credits may be selected from advanced courses (200 level) offered by the Departments of Neurosciences, Biological Sciences, Cognitive Science, and Psychology.

Courses offered by these departments can be found here.

Students may petition to receive elective credit for courses offered by other departments, or for courses taken previously, as long as they are graduate level courses directly relevant to neuroscience. To receive credit for a readings-based elective, the course must be based primarily on reading and discussion of primary literature. MSTP students automatically get 4 units of elective credit for Basic Neurology.

All petitions must include a course syllabus or reading list and should be submitted to the Chair of the Curriculum Committee or the Director of the Graduate Program for approval. Once approved, the student must send the notice of approval to the Graduate Program Coordinator so that it can be noted in his/her record.

The following is a list of recommended electives:

NEU 222 Molecular and Cellular Neuroendocrinology (course coordinator Dr. Wylie Vale)

This course examines the role of the central nervous system in controlling reproductive functions, with emphasis on the cellular mechanisms of neuroendocrine function. The lectures are given by experts on the various topics. Lectures include a basic introduction on the topic followed by a discussion of current research in the area. Winter quarter, alternate years.

NEU 263 Developmental Neurobiology (course coordinator Dr. Greg Lemke)

This course examines cellular and developmental aspects of the nervous system. Topics include neuroembryology, neuroglial cells and neuron-glia interactions, control of neuronal survival and differentiation, and plasticity and regeneration of the nervous system. Spring quarter, alternate years.

NEU 268 Molecular and Cellular Neurobiology (course coordinator Dr. Pamela Mellon)

This course focuses on the cellular and molecular basis of nervous system function. The lectures will communicate current genetic and cell biological approaches used to study the specialized structures and cell types of the nervous system. Topics include cell organelles, chromatin structure and function, cytoskeleton and membrane interactions, receptors and signal transduction, channels and pumps, cellular junctions and synapses, node of Ranvier, and neuroplasmic transport. Fall quarter, alternate years.

NEU 277 Neuropsychopharmacology (Drs. Mark A. Geyer and Ron Kuczenski)

This course examines the molecular and biochemical bases of drug and transmitter action. The course is devoted to receptor mechanisms, neuropharmacology, and drug action on excitable tissues. Spring quarter, alternate years.

NEU 221 Advanced Topics in Neuroscience

The advanced topics courses are typically entirely based around reading research papers and discussions. Different advanced topics courses are offered each year. Past courses have included:

  • Advanced cellular & synaptic physiology (Dr. Jeff Isaacson)
  • Biology of the synapse (Dr. Paul Martin)
  • Neurodegenerative diseases (Drs. Koo and Masliah)
  • Neuroinformatics (Dr. Martone)
  • Feedback and sensorimotor control (Dr. Kleinfeld)
  • Developmental neurobiology (Dr. Turner)
  • Neurotransmitter Storage Vesicle (Dr. O’Connor)
  • Visual system (Drs. Thomas Albright and Harvey J. Karten)
  • Inhibition: synapses, cells, & circuits (Dr. Ed Callaway)
  • Ion Channels (Dr. Paul Slesinger)
  • Neuropsychiatric disorders of misguide urge, impulse, and action (Dr. Swerdlow)

NEU 232 Neuroscience at the Boundaries of Neurology and Psychiatry, Part I & II (Drs. Eddie Koo and Neal Swerdlow)

This course focuses on disorders affecting the nervous system, emphasizing phenomenological and mechanistic links and common biological themes across these disorders. Clinical presentations, pathology, and basic science of selected diseases will be covered in lecture and discussion format.

Research Rounds

Research Rounds is a weekly seminar course that meets in Fall, Winter and Spring quarters, in which graduate students beyond their second year in the Program present their current research. Students in their first and second years are required to take Neurosciences Research Rounds (NEU 276).

Teaching

All students are required to perform as a teaching assistant (TA) for at least one quarter during their graduate career to develop their talents and gain experience as teachers. To this end, opportunities to lecture and to assist in laboratory exercises and demonstrations are available through a number of departments, including Neurosciences, Biology and Cognitive Science. This teaching requirement must be fulfilled before advancing to candidacy. Furthermore, as TAships are a curriculum requirement for the program, they are not a source of supplementary income. In cases where the students’ TAships provide financial support, the total annual support will remain at the standard level, currently $26,500/year. Students are encouraged to complete their TA requirement during their second or third year, and should directly contact the course instructor of the course they wish to TA.

Minor Proposition Exam

The Minor Proposition Exam is generally taken during the Fall quarter of the student’s second year. The exam must be passed by the end of the second academic year.
The exam is designed to meet two objectives:

  • To evaluate the ability of the student to propose and defend an original research project.
  • To evaluate the proficiency of the student’s general neuroscience knowledge as drawn from the Core Courses taken in the first two years of study.


The Minor Proposition Examination requires the student to select a research problem in the neurosciences and propose an experimental approach for solving it. The selected problem should be broad, requiring experimental approaches from more than one discipline, and should be outside the area of the student’s anticipated dissertation research. Students will be required to demonstrate a working knowledge of the disciplines involved in the Minor Proposition.

There are four phases to the Minor Proposition:

  • Selection of an approved topic through the production of a two-page abstract submitted to the Minor Proposition Committee.
  • Submitting a ten-page proposal in NIH small-grant format.
  • Taking an oral examination consisting of a thirty-minute presentation followed by a period of open questioning by a four-member committee, two of whom are appointed by the Minor Proposition Committee (other two members are chosen by the student). Note that the student may be examined on any aspect of the core curriculum.
  • The Chair of the students committee will submit an evaluation form to the Graduate Program Office describing the students Minor Proposition presentation and outcome of exam.

Upon passing the Minor Proposition Exam, the student is eligible to receive his/her Masters Degree (see Appendix III in the Student Handbook).

Advancement to Candidacy Examination

This exam is required by the Graduate Council of the Academic Senate to evaluate the quality of the dissertation work completed as well as the proposed additional experiments. The emphasis of the exam is on the conceptual rationale of the dissertation proposal. In addition, it is the charge of the Doctoral Committee to estimate the time required to complete the project. Passing the qualifying exam advances the student to candidacy, effectively changing his/her status from doctoral student to doctoral candidate.

The Graduate Program in Neurosciences encourages students to advance by the end of their third year, however, they must advance by the end of their fourth year. The University will not allow students to register for the fall quarter of their fifth year or receive any financial support unless they have successfully advanced to candidacy. The Graduate Council requires that students advance to candidacy a minimum of three quarters (not including summer) prior to their final dissertation defense. This requirement may be waived under special circumstances.

To take the qualifying examination, a student must maintain a minimum GPA of 3.0 in upper-division and graduate course work with no more than eight units of "F" and/or "U" grades. Additionally, the student must have grades of "B" or better in all Core Courses, fulfilled their teaching requirement, and must have completed a minimum of three academic quarters. All Core Course work must be completed before a student is permitted to advance.

In preparation for advancement, the student must put together a Doctoral Committee that is approved by the Program Director and OGSR. Names of your proposed committee members must be submitted to the Graduate Program Coordinator at least one month prior to the anticipated exam date. After review, the coordinator will send the nomination form to OGS for review and requested approval. Allow three weeks for the OGS review process. Students should not schedule their exam date until they have received final approval for the appointment of their doctoral committee by OGS.

(See Appendix IV in the Student Handbook for detailed information on criteria for selecting a Doctoral Committee.)

Dissertation Proposal

After selecting a Doctoral Committee, the student must schedule the examination and present a written dissertation proposal to the Doctoral Committee. There is no required format for the dissertation proposal, but the proposal (generally less than 10 pages)should describe the goals of the project, summarize previous work in the area, describe the experimental design, present the progress that the student has already made, and discuss future plans. The Thesis Advisor should read and approve the proposal before it is distributed to other Doctoral Committee members. The committee should have your proposal at least one week prior to the Qualifying Examination.

At the Qualifying Examination, the student is required to give an oral presentation that is followed by a period of open questioning from the committee members. When the dissertation proposal is approved, the Committee members sign the exam approval sheet (see Appendix IV in the Student Handbook, exhibit two). A $65.00 Advancement to Candidacy fee is required, in advance, to complete the paperwork. The Neurosciences Graduate Program will not cover this fee, however the students may request reimbursement from their doctoral advisor or thesis lab.

Doctoral (Thesis) Committee Meetings

In addition to the administering the Qualifying Exam, the Doctoral Committee (also called thesis committee) oversees the progress of the dissertation and administers the Final Examination. The student should schedule at least one thesis committee meeting each year during Spring Quarter (see Spring Evaluations) after Advancement to Candidacy. The Chair of the thesis committee and three additional members must sign a progress report at each meeting to indicate that the student is making adequate progress towards completing his/her dissertation (see form in Appendix X in the Student Handbook).

Defense of Dissertation

The Final Examination consists of two parts.

1. A public presentation of the dissertation work, followed by public discussion.

2. An oral defense, in closed session, with the student’s Doctoral Committee.

The student MUST contact the Graduate Program Coordinator at least one month prior to scheduling their defense/final exam. The requirements listed in the Instruction for Preparation and Submission of Doctoral Dissertations issued by the Office of Graduate Studies must be closely followed. At the conclusion of the Final Examination, all members will sign the "Final Report of the Final Examination and Filing of the Dissertation for the Degree of Doctor of Philosophy" (Appendix VI, Exhibit 1 in the Student Handbook), directly following the examination. The student delivers the form in person to obtain the appropriate signatures from the Program Director, OGS, and University Archivist.

The Ph.D. degree is conferred at the end of the quarter in which all forms are completed. The student may, if they choose, attend the graduation ceremonies held in the following June.

Support Limit
This is the maximum time during which a doctoral student is eligible for support. If the student does not complete all requirements by the end of the sixth year, (s)he may continue as a student for an additional year, but will not be eligible for financial support during that year. This includes fellowships, scholarships, and employment administered by the University and its affiliated institutions (i.e. the Salk Institute, the Burnham Institute, and the Scripps Research Institute), but does not affect financial aid loans.

Additional information about academic advising can be found in the Student Handbook.

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Page last updated: August 7, 2007


Contact Information

Graduate Program in Neurosciences
University of California, San Diego

9500 Gilman Drive 0662
La Jolla CA 92093-0662
Phone: (858) 534-3377
Fax: (858) 534-8242
E-mail: neurograd@ucsd.edu

© 2005 UCSD Graduate Program in Neurosciences.

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